Baicalin相关论文
Ferroptosis is a non-apoptotic regulated cell death caused by iron accumulation and subse-quent lipid peroxidation.Curre......
Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pa
Baicalin is a natural active ingredient isolated from Scutellariae Radix that can cross the blood-brain barrier and exhi......
Objective:To evaluate the effect of baicalin on subarachnoid hemorrhage (SAH) in rats and explore the potential mechanis......
Baicalin attenuates high fat diet-induced insulin resistance and ectopic fat storage in skeletal mus
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Characterization and evaluation in vivo of baicalin-nanocrystals prepared by an ultrasonic-homogeniz
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Role of generation on folic acid-modified poly(amidoamine)dendrimers for targeted delivery of baical
Baicalin(BAI)has been reported to exert antitumor effects.However,BAI has limited water solubility,non-specific tumor ta......
Pore Structure of Temperature-Sensitive Superporous Hydrogels and the Absorption and Release of Baic
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Preparation and Performance Research of Hemostatic Powder of Chitosan mixed with Scutellaria Baicale
In this paper,using water extraction acid sinking method to extract the active components of scutellaria baicalensis....
Baicalin attenuates bleomycin-induced pulmonary fibrosis via adenosine A2a receptor related TGF-β1-i
目的 Baicalin has been reported to have anti-fibrosis effect; however, its mechanism still remains to be elucidated.Adeno......
Both the down-regulation of c-myc and activation of apoptosis pathway are involved in anti-prolifera
Aim: Baicalin has been documented to induce apoptosis of leukemia-derived T cell line,Jurkat cells,via mitochondrial pat......
Study of baicalin on sympathoexcitatory activity induced by myocardial ischemia via P2X2 receptor in
Objective Myocardial ischemia(MI)can induce myocardial tissues releasing large quantity of ATP,which activated P2X2 rece......
Background: As one of the classic medicine couples,Baikal Skullcap Root and Coptis Root have been reported that precipit......
The neuroprotective effects of baicalin on ethanol-induced impairment via anti-oxidative and anti-ap
Baicalin is a major bioactive ingredient from the roots of Scutellaria baicalensis Georgi and has various pharmacologica......
OBJECTIVE To investigate the effects and molecular mechanisms of Baicalin, a natural flavonoid compound derived from Scu......
Inhibitory effect of baicalin on the plasma protein binding and CYP1A2 activity induce the pharmacok
Aim: To elucidate the effect of baicalin on the pharmacokinetics of theophylline in rats, focusing on plasma protein bin......
Contribution of baicalin on the plasma protein binding displacement and CYP3A activity inhibition to
Aim: Baicalin purified from the root of Radix scutellariae has been widely used in clinical practices.This study aimed t......
Tanreqing solution(TRQ)based on the traditional Chinese medicine,is used to cure upper respiratory tract infections.In p......
Aim: Baicalin can improve insulin sensitivity, but little is known about the underlying mechanism.Whether baicalin preve......
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As one of natural flavonoids, baicalin is the main active ingredient of scutellaria.Modern pharmacological studies have ......
Inhibition of NF-κB and CCR7/CCL19/CCL21 contribute to the attenuation of inflammation by Baicalin i
Baicalin, extracted and purified from the Chinese medicinal plant ScutellariabaicalensisGeorgi (Chinese name: Huang Qin)......
Variation of pathways and networks profiles reveals the differential pharmacological mechanisms of e
Using a systems pharmacology strategy, this study evaluated the unique pharmacological characteristics of three differen......
Baicalin significantly inhibit the herpes simplex virus type 1 alkaline nuclease and stop herpes sim
AIM In order to find an effective antiviral drug against the herpes simplex virus type 1 (HSV-1) and understand its mech......
目的:建立同时测定金振口服液中黄芩苷和甘草酸含量测定的HPLC 方法。方法:采用Waters C18(150 mm×4.6 mm,5 μm)色谱柱,流动相为乙腈......
目的:高山研究红景天挥发油、氮酮及丙二醇对黄芩苷体外透皮吸收的 影响。方法:以离体小鼠腹部皮肤为透皮屏障,采用改良Franz 扩散......
Baicalin prompts migration of neural progenitor cell by stimulating hypoxia-induced astrocyte in vit
The migration of transplanted neural progenitor cell (NPC) or endogenesis NPC to damagedsections in the central nervous ......
The mechanism of baicalin inhibits the migration of vascular smooth muscle cells in vitro and in viv
The migration of vascular smooth muscle cells (VSMCs) across the internal elastic lamina from the tunica media is a ......
Extensive iron deposition has been demced in the brains of Parkinson’S disease(PD)patients,and a few animal experiments ......
目的探讨黄芩苷(baicalin,BA)对慢性不可预知温和刺激(chronic unpredictable mild stimulus,CUMS)模型小鼠抑郁行为及细胞外调节蛋......
目的探讨不同剂量黄芩苷(BAI)对脓毒症小鼠急性肾损伤(AKI)的保护作用及机制。方法按随机数字表法将100只实验小鼠分为假手术组(Sham组)......
目的研究局部应用不同浓度黄芩苷对实验性牙周炎的影响。方法 42只SD大鼠,随机分为空白对照组(NG组)、阴性对照组(EP组)、甘油溶剂......
目的研究黄芩苷在体外对牙龈卟啉单胞菌(Porphyromonas gingivalis, P.g)、具核梭杆菌(Fusobacterium nucleatum, F.n)及伴放线聚......
Characterization and evaluation in vivo of baicalin-nanocrystals prepared by an ultrasonic-homogeniz
试图用 nanocrystal 改进 baicalin 的吸收和 bioavailability (或 nanosuspension ) 药交货系统。方法 A 双人脚踏车,弄干技术的 u......
Comparison of the Network Structural Characteristics of Calcium Signaling Pathway in Cerebral Ischem
Objective:To explore the network control mechanism of the calcium signaling pathway in cerebral ischemic injury after in......
Effect of baicalin and berberine on transport of nimodipine on primarycultured, rat brain microvascu
目的:调查 baicalin 和 berberine 是否越过血大脑障碍( BBB )影响运输 ofnimodipine ( NMD ) .Methods :主要有教养,老鼠大脑 micr......
[Objective] The aim was to prepare sustained-release microcapsules of baicalin,as well as to design and optimize the pre......
目的考察聚乙二醇400(PEG400)对黄芩苷在大鼠体内药动学的影响。方法将大鼠随机分为黄芩苷组和PEG400组,黄芩苷组大鼠单独灌胃给予黄......
目的探讨黄芩苷对小鼠吗啡行为敏化的影响。方法测定小鼠的自主活动,观察黄芩苷对小鼠自主活动的影响。分别采用单次给予吗啡(10 mg......
Baicalin and jasminoidin effects on gene expression and compatibility in the hippocampus following f
The compound traditional Chinese medicine Qingkailing, which is an ingredient used to treat cerebral ischemia, has been ......
Baicalin suppresses iron accumulation after substantia nigra injury:relationship between iron concen
Previous studies have shown that baicalin prevented iron accumulation after substantia nigra injury, reduced divalent me......
目的建立复方芪防颗粒的质量标准。方法采用薄层色谱法对复方芪防颗粒中的药材防风、苦参、黄柏的成分进行定性鉴别;并应用薄层扫描......
目的 研究黄芩苷对大鼠卡氏肺孢子虫肺炎(PCP)的预防效果.方法 以每周2次、连续6周皮下注射地塞米松3.5 mg/只,建立清洁级SD大鼠PC......
Comparison of the Network Structural Characteristics of Calcium Signaling Pathway in Cerebral Ischem
Objective:To explore the network control mechanism of the calcium signaling pathway in cerebral ischemic injury after in......
Baicalin extracted from Huangqin (Radix Scutellariae Baicalensis) induces apoptosis in gastric cance
OBJECTIVE:To evaluate the effects of baicalin in human gastric cancer cells,including apoptosis-inducing effects,and to ......
目的 探讨黄芩苷对创伤性休克患者血清炎性因子和氧自由基代谢的影响.方法38例创伤性休克的患者入院后予黄芩苷200 mg静脉注射,测......
目的:制备复方氟康唑凝胶并建立质量控制方法。方法:以氟康唑配伍黄芩苷制成凝胶,采用HPLC法测定凝胶中氟康唑及黄芩苷的含量,并考......
目的:同时测定肝血管瘤活血胶囊中栀子苷和黄芩苷含量。方法:选用的色谱柱为Agilent Eclipse XDB-C_(18)(150 mm×4.6 mm,5μm);流......